CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.470 | D-amino Acid Aminotransferase; Chain A, domain 1 |
|
3.30.470.30 | DNA ligase/mRNA capping enzyme |
Domain Context
CATH Clusters
| Superfamily | DNA ligase/mRNA capping enzyme |
| Functional Family | mRNA-capping enzyme subunit alpha |
Enzyme Information
| 2.7.7.50 |
mRNA guanylyltransferase.
based on mapping to UniProt P40997
GTP + (5')pp-Pur-mRNA = diphosphate + G(5')ppp-Pur-mRNA.
-!- Can modify also synthetic poly(A) and poly(G) to form the structures m(7)G(5')pppAn and m(7)G(5')pppGn.
|
UniProtKB Entries (1)
| P40997 |
MCE1_SCHPO
Schizosaccharomyces pombe 972h-
MRNA-capping enzyme subunit alpha
|
PDB Structure
| PDB | 4PZ7 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
How an mRNA capping enzyme reads distinct RNA polymerase II and Spt5 CTD phosphorylation codes.
Genes Dev.
|
