CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.90 | Alpha-Beta Complex |
|
3.90.360 | Histone Acetyltransferase; domain 1 |
|
3.90.360.10 | Histone acetyl transferase 1 (HAT1), N-terminal domain |
Domain Context
CATH Clusters
| Superfamily | Histone acetyl transferase 1 (HAT1), N-terminal domain |
| Functional Family | Histone acetyltransferase type B catalytic subunit |
Enzyme Information
| 2.3.1.48 |
Histone acetyltransferase.
based on mapping to UniProt Q12341
Acetyl-CoA + [protein]-L-lysine = CoA + [protein]-N(6)-acetyl-L-lysine.
-!- A group of enzymes acetylating histones. -!- Several of the enzymes can also acetylate lysines in other proteins.
|
UniProtKB Entries (2)
| V8PGJ1 |
V8PGJ1_OPHHA
Ophiophagus hannah
Histone H4
|
| P39984 |
HAT2_YEAST
Saccharomyces cerevisiae S288C
Histone acetyltransferase type B subunit 2
|
PDB Structure
| PDB | 4PSW |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Hat2p recognizes the histone H3 tail to specify the acetylation of the newly synthesized H3/H4 heterodimer by the Hat1p/Hat2p complex
Genes Dev.
|
