CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.10 | Roll |
|
3.10.20 | Ubiquitin-like (UB roll) |
|
3.10.20.90 | Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 |
Domain Context
CATH Clusters
| Superfamily | Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 |
| Functional Family | Merlin isoform 2 |
Enzyme Information
UniProtKB Entries (2)
| P46662 |
MERL_MOUSE
Mus musculus
Merlin
|
| Q9Y4B6 |
DCAF1_HUMAN
Homo sapiens
DDB1- and CUL4-associated factor 1
|
PDB Structure
| PDB | 4P7I |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structural basis of the binding of Merlin FERM domain to the E3 ubiquitin ligase substrate adaptor DCAF1.
J.Biol.Chem.
|
