CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.533 | Death Domain, Fas |
|
1.10.533.10 | Death Domain, Fas |
Domain Context
CATH Clusters
| Superfamily | Death Domain, Fas |
| Functional Family | Probable ATP-dependent RNA helicase DDX58 |
Enzyme Information
| 3.6.4.13 |
RNA helicase.
based on mapping to UniProt O95786
ATP + H(2)O = ADP + phosphate.
-!- RNA helicases utilize the energy from ATP hydrolysis to unwind RNA. -!- Some of them unwind RNA with a 3' to 5' polarity, other show 5' to 3' polarity. -!- Some helicases unwind DNA as well as RNA. -!- May be identical with EC 3.6.4.12 (DNA helicase).
|
UniProtKB Entries (1)
| O95786 |
DDX58_HUMAN
Homo sapiens
Probable ATP-dependent RNA helicase DDX58
|
PDB Structure
| PDB | 4P4H |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Molecular Imprinting as a Signal-Activation Mechanism of the Viral RNA Sensor RIG-I.
Mol.Cell
|