CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.800 | Anticodon-binding domain |
Domain Context
CATH Clusters
| Superfamily | Anticodon-binding domain |
| Functional Family | Threonine--tRNA ligase 2, cytoplasmic |
Enzyme Information
| 6.1.1.3 |
Threonine--tRNA ligase.
based on mapping to UniProt P26639
ATP + L-threonine + tRNA(Thr) = AMP + diphosphate + L-threonyl-tRNA(Thr).
|
UniProtKB Entries (1)
| P26639 |
SYTC_HUMAN
Homo sapiens
Threonine--tRNA ligase, cytoplasmic
|
PDB Structure
| PDB | 4P3N |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structural basis for full-spectrum inhibition of translational functions on a tRNA synthetase.
Nat Commun
|
