CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.930 | BirA Bifunctional Protein; domain 2 |
|
3.30.930.10 | Bira Bifunctional Protein; Domain 2 |
Domain Context
CATH Clusters
| Superfamily | Bira Bifunctional Protein; Domain 2 |
| Functional Family | Threonine--tRNA ligase 2, cytoplasmic |
Enzyme Information
| 6.1.1.3 |
Threonine--tRNA ligase.
based on mapping to UniProt P26639
ATP + L-threonine + tRNA(Thr) = AMP + diphosphate + L-threonyl-tRNA(Thr).
|
UniProtKB Entries (1)
| P26639 |
SYTC_HUMAN
Homo sapiens
Threonine--tRNA ligase, cytoplasmic
|
PDB Structure
| PDB | 4P3N |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structural basis for full-spectrum inhibition of translational functions on a tRNA synthetase.
Nat Commun
|
