CATH Classification
Level | CATH Code | Description |
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3 | Alpha Beta |
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3.20 | Alpha-Beta Barrel |
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3.20.20 | TIM Barrel |
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3.20.20.70 | Aldolase class I |
Domain Context
CATH Clusters
Superfamily | Aldolase class I |
Functional Family |
Enzyme Information
4.1.1.48 |
Indole-3-glycerol-phosphate synthase.
based on mapping to UniProt Q06121
1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate = 1-C- (3-indolyl)-glycerol 3-phosphate + CO(2) + H(2)O.
-!- In some organisms, this enzyme is part of a multifunctional protein together with one or more components of the system for biosynthesis of tryptophan (EC 2.4.2.18, EC 4.1.3.27, EC 4.2.1.20 and EC 5.3.1.24).
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UniProtKB Entries (1)
Q06121 |
TRPC_SACS2
Saccharolobus solfataricus P2
Indole-3-glycerol phosphate synthase
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PDB Structure
PDB | 4OU1 |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Small molecule probes to quantify the functional fraction of a specific protein in a cell with minimal folding equilibrium shifts.
Proc.Natl.Acad.Sci.USA
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