CATH Classification

Domain Context

CATH Clusters

Superfamily NAD(P)-binding Rossmann-like Domain
Functional Family

Enzyme Information

1.1.1.169
2-dehydropantoate 2-reductase.
based on mapping to UniProt P9WIL1
(R)-pantoate + NADP(+) = 2-dehydropantoate + NADPH.

UniProtKB Entries (1)

P9WIL1
PANE_MYCTU
Mycobacterium tuberculosis H37Rv
Putative 2-dehydropantoate 2-reductase

PDB Structure

PDB 4OL9
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal Structure of putative 2-dehydropantoate 2-reductase PanE from Mycobacterium tuberculosis complexed with NADP and oxamate
Dranow, D.M., Wernimont, A.K., Abendroth, A., Pierce, P.G., Bullen, J., Edwards, T.E., Lorimer, D., Seattle Structural Genomics Center for Infectious Disease
To be Published
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