CATH Domain 4ogcA01

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.420	Nucleotidyltransferase; domain 5
	3.30.420.10	Ribonuclease H-like superfamily/Ribonuclease H

Domain Context

CATH Clusters

Superfamily	Ribonuclease H-like superfamily/Ribonuclease H
Functional Family

Enzyme Information

3.1.-.-

Acting on ester bonds.

based on mapping to UniProt J3F2B0

UniProtKB Entries (1)

CAS9_ACTNH

Actinomyces naeslundii str. Howell 279

CRISPR-associated endonuclease Cas9

PDB Structure

PDB	4OGC
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structures of Cas9 endonucleases reveal RNA-mediated conformational activation. Jinek, M., Jiang, F., Taylor, D.W., Sternberg, S.H., Kaya, E., Ma, E., Anders, C., Hauer, M., Zhou, K., Lin, S., Kaplan, M., Iavarone, A.T., Charpentier, E., Nogales, E., Doudna, J.A. Science