CATH Domain 4o1pA01

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.25	Alpha Horseshoe
	1.25.40	Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat
	1.25.40.20	Ankyrin repeat-containing domain

Domain Context

CATH Clusters

Superfamily	Ankyrin repeat-containing domain
Functional Family

Enzyme Information

UniProtKB Entries (1)

A5H025_PIG

Sus scrofa

Ribonuclease L

PDB Structure

PDB	4O1P
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Dimeric structure of pseudokinase RNase L bound to 2-5A reveals a basis for interferon-induced antiviral activity. Huang, H., Zeqiraj, E., Dong, B., Jha, B.K., Duffy, N.M., Orlicky, S., Thevakumaran, N., Talukdar, M., Pillon, M.C., Ceccarelli, D.F., Wan, L.C., Juang, Y.C., Mao, D.Y., Gaughan, C., Brinton, M.A., Perelygin, A.A., Kourinov, I., Guarne, A., Silverman, R.H., Sicheri, F. Mol.Cell