CATH Classification

Domain Context

CATH Clusters

Superfamily Phosphorylase Kinase; domain 1
Functional Family Aurora kinase A

Enzyme Information

2.7.11.1
Non-specific serine/threonine protein kinase.
based on mapping to UniProt O14965
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.

UniProtKB Entries (1)

O14965
AURKA_HUMAN
Homo sapiens
Aurora kinase A

PDB Structure

PDB 4O0W
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Functional Role of Conserved HxD-histidine in the Catalytic Core of Protein Kinase
Zhang, L., Wang, J., Hou, L., Cao, P., Wu, L., Zang, Y., Ding, J., Li, J.
To be Published
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