CATH Classification

Domain Context

CATH Clusters

Superfamily 3.40.630.30
Functional Family Histone acetyltransferase KAT2A

Enzyme Information

2.3.1.48
Histone acetyltransferase.
based on mapping to UniProt Q92831
Acetyl-CoA + [protein]-L-lysine = CoA + [protein]-N(6)-acetyl-L-lysine.
-!- A group of enzymes acetylating histones. -!- Several of the enzymes can also acetylate lysines in other proteins.
2.3.1.57
Diamine N-acetyltransferase.
based on mapping to UniProt Q92831
Acetyl-CoA + an alkane-alpha,omega-diamine = CoA + an N-acetyldiamine.
-!- Acts on 1,3-diaminopropane, 1,5-diaminopentane, putrescine, spermidine (forming N(1)- and N(8)-acetylspermidine), spermine, N(1)- acetylspermidine and N(8)-acetylspermidine.

UniProtKB Entries (1)

Q92831
KAT2B_HUMAN
Homo sapiens
Histone acetyltransferase KAT2B

PDB Structure

PDB 4NSQ
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Dimeric structure of p300/CBP associated factor.
Shi, S., Lin, J., Cai, Y., Yu, J., Hong, H., Ji, K., Downey, J.S., Lu, X., Chen, R., Han, J., Han, A.
Bmc Struct.Biol.