CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.90 | Alpha-Beta Complex |
|
3.90.190 | Protein-Tyrosine Phosphatase; Chain A |
|
3.90.190.10 | Protein tyrosine phosphatase superfamily |
Domain Context
CATH Clusters
| Superfamily | Protein tyrosine phosphatase superfamily |
| Functional Family | Tyrosine-protein phosphatase non-receptor type 12 |
Enzyme Information
| 3.1.3.48 |
Protein-tyrosine-phosphatase.
based on mapping to UniProt Q99952
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.
-!- Dephosphorylates O-phosphotyrosine groups in phosphoproteins, such as the products of EC 2.7.10.2.
|
UniProtKB Entries (1)
| Q99952 |
PTN18_HUMAN
Homo sapiens
Tyrosine-protein phosphatase non-receptor type 18
|
PDB Structure
| PDB | 4NND |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structural basis of PTPN18 fingerprint on distinct HER2 tyrosine phosphorylation sites
To be Published
|