CATH Classification
Level | CATH Code | Description |
---|---|---|
2 | Mainly Beta | |
2.10 | Ribbon | |
2.10.25 | Laminin | |
2.10.25.10 | Laminin |
Domain Context
CATH Clusters
Superfamily | Laminin |
Functional Family | Coagulation factor VII |
Enzyme Information
3.4.21.21 |
Coagulation factor VIIa.
based on mapping to UniProt P08709
Selective cleavage of Arg-|-Ile bond in factor X to form factor Xa.
-!- Formed from the precursor factor VII. -!- The cattle enzyme is more readily inhibited by diisopropyl fluorophosphate than the human. -!- Belongs to peptidase family S1.
|
UniProtKB Entries (1)
P08709 |
FA7_HUMAN
Homo sapiens
Coagulation factor VII
|
PDB Structure
PDB | 4NGA |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Design and Synthesis of Phenylpyrrolidine Phenylglycinamides As Highly Potent and Selective TF-FVIIa Inhibitors.
ACS Med Chem Lett
|