CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.30 | 2-Layer Sandwich | |
3.30.930 | BirA Bifunctional Protein; domain 2 | |
3.30.930.10 | Bira Bifunctional Protein; Domain 2 |
Domain Context
CATH Clusters
Superfamily | Bira Bifunctional Protein; Domain 2 |
Functional Family |
Enzyme Information
6.1.1.15 |
Proline--tRNA ligase.
based on mapping to UniProt Q8I5R7
ATP + L-proline + tRNA(Pro) = AMP + diphosphate + L-prolyl-tRNA(Pro).
|
UniProtKB Entries (1)
Q8I5R7 |
SYP_PLAF7
Plasmodium falciparum 3D7
Proline--tRNA ligase
|
PDB Structure
PDB | 4NCX |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Biochemical and Structural Characterization of Selective Allosteric Inhibitors of the Plasmodium falciparum Drug Target, Prolyl-tRNA-synthetase.
ACS Infect Dis
|