CATH Domain 4n4wA01

Level	CATH Code	Description
	1	Mainly Alpha
	1.20	Up-down Bundle
	1.20.120	Four Helix Bundle (Hemerythrin (Met), subunit A)
	1.20.120.10	Cytochrome c/b562

Superfamily	Cytochrome c/b562
Functional Family

Q99835	SMO_HUMAN Homo sapiens Smoothened homolog
Q0SXH8	Q0SXH8_SHIF8 Shigella flexneri 5 str. 8401 Cytochrome b(562)

PDB	4N4W
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structural basis for Smoothened receptor modulation and chemoresistance to anticancer drugs. Wang, C., Wu, H., Evron, T., Vardy, E., Han, G.W., Huang, X.P., Hufeisen, S.J., Mangano, T.J., Urban, D.J., Katritch, V., Cherezov, V., Caron, M.G., Roth, B.L., Stevens, R.C. Nat Commun