CATH Domain 4n2kA02

Level	CATH Code	Description
	2	Mainly Beta
	2.60	Sandwich
	2.60.40	Immunoglobulin-like
	2.60.40.1700	Protein-arginine deiminase, central domain

Superfamily	Protein-arginine deiminase, central domain
Functional Family	Protein-arginine deiminase type-2

3.5.3.15

Protein-arginine deiminase.

based on mapping to UniProt Q9Y2J8

Protein L-arginine + H(2)O = protein L-citrulline + NH(3).

-!- Also acts on N-acyl-L-arginine and, more slowly, on L-arginine esters.

PADI2_HUMAN

Homo sapiens

Protein-arginine deiminase type-2

PDB	4N2K
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Protein arginine deiminase 2 binds calcium in an ordered fashion: implications for inhibitor design. Slade, D.J., Fang, P., Dreyton, C.J., Zhang, Y., Fuhrmann, J., Rempel, D., Bax, B.D., Coonrod, S.A., Lewis, H.D., Guo, M., Gross, M.L., Thompson, P.R. Acs Chem.Biol.