1 keywords

CATH Domain 4mvwA01

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.40 3-Layer(aba) Sandwich
Topology 3.40.50 Rossmann fold
Homologous Superfamily 3.40.50.620 HUPs

Domain Context

CATH Clusters

Superfamily HUPs
Functional Family methionine--tRNA ligase, mitochondrial

Enzyme Information

UniProtKB Entries (1)

Q38C91
Q38C91_TRYB2
Trypanosoma brucei brucei TREU927
Methionyl-tRNA synthetase, putative

PDB Structure

PDB 4MVW
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structures of Trypanosoma brucei Methionyl-tRNA Synthetase with Urea-Based Inhibitors Provide Guidance for Drug Design against Sleeping Sickness.
Koh, C.Y., Kim, J.E., Wetzel, A.B., de van der Schueren, W.J., Shibata, S., Ranade, R.M., Liu, J., Zhang, Z., Gillespie, J.R., Buckner, F.S., Verlinde, C.L., Fan, E., Hol, W.G.
Plos Negl Trop Dis