CATH Domain 4msuB01

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.50	Rossmann fold
	3.40.50.10490	Glucose-6-phosphate isomerase like protein; domain 1

Domain Context

CATH Clusters

Superfamily	Glucose-6-phosphate isomerase like protein; domain 1
Functional Family	Glucokinase regulatory protein

Enzyme Information

UniProtKB Entries (1)

GCKR_HUMAN

Homo sapiens

Glucokinase regulatory protein

PDB Structure

PDB	4MSU
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Small Molecule Disruptors of the Glucokinase-Glucokinase Regulatory Protein Interaction: 1. Discovery of a Novel Tool Compound for in Vivo Proof-of-Concept. Ashton, K.S., Andrews, K.L., Bryan, M.C., Chen, J., Chen, K., Chen, M., Chmait, S., Croghan, M., Cupples, R., Fotsch, C., Helmering, J., Jordan, S.R., Kurzeja, R.J., Michelsen, K., Pennington, L.D., Poon, S.F., Sivits, G., Van, G., Vonderfecht, S.L., Wahl, R.C., Zhang, J., Lloyd, D.J., Hale, C., St Jean, D.J. J.Med.Chem.