CATH Domain 4mi4A00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.630	Aminopeptidase
	3.40.630.30	Gcn5-related N-acetyltransferase (GNAT)

Domain Context

CATH Clusters

Superfamily	3.40.630.30
Functional Family	Spermidine N(1)-acetyltransferase

Enzyme Information

2.3.1.57

Diamine N-acetyltransferase.

based on mapping to UniProt Q9KL03

Acetyl-CoA + an alkane-alpha,omega-diamine = CoA + an N-acetyldiamine.

-!- Acts on 1,3-diaminopropane, 1,5-diaminopentane, putrescine, spermidine (forming N(1)- and N(8)-acetylspermidine), spermine, N(1)- acetylspermidine and N(8)-acetylspermidine.

UniProtKB Entries (1)

Q9KL03

ATDA_VIBCH

Vibrio cholerae O1 biovar El Tor str. N16961

Spermidine N(1)-acetyltransferase

PDB Structure

PDB	4MI4
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	A Novel Polyamine Allosteric Site of SpeG from Vibrio cholerae Is Revealed by Its Dodecameric Structure. Filippova, E.V., Kuhn, M.L., Osipiuk, J., Kiryukhina, O., Joachimiak, A., Ballicora, M.A., Anderson, W.F. J.Mol.Biol.