CATH Classification

Domain Context

CATH Clusters

Superfamily 3.40.50.10130
Functional Family Fanconi anemia, complementation group M

Enzyme Information

3.6.4.13
RNA helicase.
based on mapping to UniProt Q8IYD8
ATP + H(2)O = ADP + phosphate.
-!- RNA helicases utilize the energy from ATP hydrolysis to unwind RNA. -!- Some of them unwind RNA with a 3' to 5' polarity, other show 5' to 3' polarity. -!- Some helicases unwind DNA as well as RNA. -!- May be identical with EC 3.6.4.12 (DNA helicase).

UniProtKB Entries (1)

Q9BTP7
FAP24_HUMAN
Homo sapiens
Fanconi anemia core complex-associated protein 24

PDB Structure

PDB 4M6W
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural insights into the functions of the FANCM-FAAP24 complex in DNA repair.
Yang, H., Zhang, T., Tao, Y., Wang, F., Tong, L., Ding, J.
Nucleic Acids Res.
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