CATH Classification

Domain Context

CATH Clusters

Superfamily Class II aldolase/adducin N-terminal domain
Functional Family Methylthioribulose-1-phosphate dehydratase

Enzyme Information

4.2.1.109
Methylthioribulose 1-phosphate dehydratase.
based on mapping to UniProt Q96GX9
S-methyl-5-thio-D-ribulose 1-phosphate = 5-(methylthio)-2,3-dioxopentyl phosphate + H(2)O.
-!- This enzyme forms part of the methionine salvage pathway.

UniProtKB Entries (1)

Q96GX9
MTNB_HUMAN
Homo sapiens
Methylthioribulose-1-phosphate dehydratase

PDB Structure

PDB 4M6R
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural and biochemical basis for the inhibition of cell death by APIP, a methionine salvage enzyme.
Kang, W., Hong, S.H., Lee, H.M., Kim, N.Y., Lim, Y.C., Le, L.T.M., Lim, B., Kim, H.C., Kim, T.Y., Ashida, H., Yokota, A., Hah, S.S., Chun, K.H., Jung, Y.K., Yang, J.K.
Proc.Natl.Acad.Sci.USA