CATH Classification

Domain Context

CATH Clusters

Superfamily 2.120.10.10
Functional Family Exo-alpha-sialidase

Enzyme Information

3.2.1.18
Exo-alpha-sialidase.
based on mapping to UniProt Q4WQS0
Hydrolysis of alpha-(2->3)-, alpha-(2->6)-, alpha-(2->8)- glycosidic linkages of terminal sialic acid residues in oligosaccharides, glycoproteins, glycolipids, colominic acid and synthetic substrates.
-!- The enzyme does not act on 4-O-acetylated sialic acids. -!- An endo-alpha-sialidase activity is listed as EC 3.2.1.129. -!- See also EC 4.2.2.15.

UniProtKB Entries (1)

Q4WQS0
SIA_ASPFU
Aspergillus fumigatus Af293
Exo-alpha-sialidase

PDB Structure

PDB 4M4U
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Active site mutants of a fungal KDNase
Yeung, J.Y., Telford, J.C., Shidmoossavee, F.S., Bennet, A.J., Taylor, G.L., Moore, M.M.
To be Published