CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.40 | Beta Barrel |
|
2.40.260 | Sortase; Chain: A; |
|
2.40.260.10 | Sortase |
Domain Context
CATH Clusters
| Superfamily | Sortase |
| Functional Family |
Enzyme Information
| 3.4.22.71 |
Sortase B.
based on mapping to UniProt A0A0H2XI76
The enzyme catalyzes a cell wall sorting reaction in which a surface protein with a sorting signal containing a NPXTN motif is cleaved between the Thr and Asn residue. The resulting threonine carboxyl end of the protein is covalently attached to a pentaglycine cross-bridge of peptidoglycan.
-!- Belongs to peptidase family C60.
|
UniProtKB Entries (1)
| A0A0H2XI76 |
A0A0H2XI76_STAA3
Staphylococcus aureus subsp. aureus USA300
Sortase B
|
PDB Structure
| PDB | 4LFD |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structural and Computational Studies of the Staphylococcus aureus Sortase B-Substrate Complex Reveal a Substrate-stabilized Oxyanion Hole.
J.Biol.Chem.
|