CATH Domain 4l5iA01

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.10	Arc Repressor Mutant, subunit A
	1.10.10.10	Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain

Domain Context

CATH Clusters

Superfamily	Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain
Functional Family	LsrR family transcriptional regulator

Enzyme Information

UniProtKB Entries (1)

LSRR_ECOLI

Escherichia coli K-12

Transcriptional regulator LsrR

PDB Structure

PDB	4L5I
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Crystal Structures of the LsrR Proteins Complexed with Phospho-AI-2 and Two Signal-Interrupting Analogues Reveal Distinct Mechanisms for Ligand Recognition. Ha, J.H., Eo, Y., Grishaev, A., Guo, M., Smith, J.A., Sintim, H.O., Kim, E.H., Cheong, H.K., Bentley, W.E., Ryu, K.S. J.Am.Chem.Soc.