CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.30 | 2-Layer Sandwich | |
3.30.505 | SHC Adaptor Protein | |
3.30.505.10 | SH2 domain |
Domain Context
CATH Clusters
Superfamily | SH2 domain |
Functional Family | Phosphatidylinositol 3-kinase regulatory subunit alpha |
Enzyme Information
UniProtKB Entries (1)
P42336 |
PK3CA_HUMAN
Homo sapiens
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
|
PDB Structure
PDB | 4L1B |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Crystal Structures of PI3K alpha Complexed with PI103 and Its Derivatives: New Directions for Inhibitors Design.
ACS Med Chem Lett
|