CATH Domain 4l19A00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.390	Collagenase (Catalytic Domain)
	3.40.390.10	Collagenase (Catalytic Domain)

Domain Context

CATH Clusters

Superfamily	Collagenase (Catalytic Domain)
Functional Family	Collagenase 3

Enzyme Information

3.4.24.-

Metalloendopeptidases.

based on mapping to UniProt P45452

UniProtKB Entries (1)

MMP13_HUMAN

Homo sapiens

Collagenase 3

PDB Structure

PDB	4L19
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Characterization of selective exosite-binding inhibitors of matrix metalloproteinase 13 that prevent articular cartilage degradation in vitro. Spicer, T.P., Jiang, J., Taylor, A.B., Choi, J.Y., Hart, P.J., Roush, W.R., Fields, G.B., Hodder, P.S., Minond, D. J.Med.Chem.