CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.390 | Neutral Protease; domain 2 |
|
1.10.390.10 | Neutral Protease Domain 2 |
Domain Context
CATH Clusters
| Superfamily | Neutral Protease Domain 2 |
| Functional Family | Glutamyl aminopeptidase |
Enzyme Information
| 3.4.11.7 |
Glutamyl aminopeptidase.
based on mapping to UniProt Q07075
Release of N-terminal glutamate (and to a lesser extent aspartate) from a peptide.
-!- Also acts on L-alpha-glutamyl-peptides. -!- Calcium-activated and generally membrane-bound. -!- Belongs to peptidase family M1.
|
UniProtKB Entries (1)
| Q07075 |
AMPE_HUMAN
Homo sapiens
Glutamyl aminopeptidase
|
PDB Structure
| PDB | 4KX9 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structural insights into central hypertension regulation by human aminopeptidase a.
J.Biol.Chem.
|
