CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.47 | Peroxisomal Thiolase; Chain A, domain 1 |
|
3.40.47.10 | Thiolase/Chalcone synthase |
Domain Context
CATH Clusters
| Superfamily | 3.40.47.10 |
| Functional Family | 3-oxoacyl-ACP synthase III |
Enzyme Information
| 2.3.3.20 |
Acyl-CoA:acyl-CoA alkyltransferase.
based on mapping to UniProt Q8PDX2
2 an acyl-CoA + H(2)O = a (2R)-2-alkyl-3-oxoalkanoate + 2 CoA.
-!- The enzyme, found in certain bacterial species, catalyzes a head- to-head non-decarboxylative Claisen condensation of two acyl-CoA molecules, resulting in formation of a 2-alkyl-3-oxoalkanoic acid. -!- It is part of a pathway for the production of olefins.
|
UniProtKB Entries (1)
| Q8PDX2 |
OLEA_XANCP
Xanthomonas campestris pv. campestris str. ATCC 33913
Acyl-CoA:acyl-CoA alkyltransferase
|
PDB Structure
| PDB | 4KU2 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Substrate Trapping in Crystals of the Thiolase OleA Identifies Three Channels That Enable Long Chain Olefin Biosynthesis.
J.Biol.Chem.
|