CATH Classification

Domain Context

CATH Clusters

Superfamily Thymidylate synthase/dCMP hydroxymethylase domain
Functional Family Thymidylate synthase

Enzyme Information

UniProtKB Entries (0)

PDB Structure

PDB 4KNZ
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Mg(2+) binds to the surface of thymidylate synthase and affects hydride transfer at the interior active site.
Wang, Z., Sapienza, P.J., Abeysinghe, T., Luzum, C., Lee, A.L., Finer-Moore, J.S., Stroud, R.M., Kohen, A.
J.Am.Chem.Soc.