CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.40 | 3-Layer(aba) Sandwich | |
3.40.630 | Aminopeptidase | |
3.40.630.30 | Gcn5-related N-acetyltransferase (GNAT) |
Domain Context
CATH Clusters
Superfamily | 3.40.630.30 |
Functional Family | N-acetylglutamate synthase, mitochondrial |
Enzyme Information
2.3.1.1 |
Amino-acid N-acetyltransferase.
based on mapping to UniProt Q8N159
Acetyl-CoA + L-glutamate = CoA + N-acetyl-L-glutamate.
-!- Also acts with L-aspartate and, more slowly, with some other amino acids.
|
UniProtKB Entries (1)
Q8N159 |
NAGS_HUMAN
Homo sapiens
N-acetylglutamate synthase, mitochondrial
|
PDB Structure
PDB | 4K30 |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Crystal structure of the N-acetyltransferase domain of human N-acetyl-L-glutamate synthase in complex with N-acetyl-L-glutamate provides insights into its catalytic and regulatory mechanisms.
Plos One
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