CATH Domain 4j7fA01

Level	CATH Code	Description
	2	Mainly Beta
	2.20	Single Sheet
	2.20.110	Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain
	2.20.110.10	Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain

Superfamily	Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain
Functional Family	Histone-lysine N-methyltransferase SETD7

2.1.1.43

Histone-lysine N-methyltransferase.

based on mapping to UniProt Q8WTS6

S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].

SETD7_HUMAN

Homo sapiens

Histone-lysine N-methyltransferase SETD7

PDB	4J7F
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Methyl CH O Hydrogen Bonds Orchestrate AdoMet-Dependent Methylation Horowitz, S., Dirk, L.M.A., Yesselman, J.D., Nimtz, J.S., Del Rizzo, P.A., Vander Meulen, K.A., Butcher, S.E., Mehl, R.A., Houtz, R.L., Al-Hashimi, H.M., Trievel, R.C. To be Published