CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.40 | 3-Layer(aba) Sandwich | |
3.40.50 | Rossmann fold | |
3.40.50.20 |
Domain Context
CATH Clusters
Superfamily | 3.40.50.20 |
Functional Family | UDP-2,3-diacylglucosamine pyrophosphatase LpxI |
Enzyme Information
3.6.1.54 |
UDP-2,3-diacylglucosamine diphosphatase.
based on mapping to UniProt A0A0H3C8Q1
UDP-2-N,3-O-bis((3R)-3-hydroxytetradecanoyl)-alpha-D-glucosamine + H(2)O = 2-N,3-O-bis((3R)-3-hydroxytetradecanoyl)-alpha-D-glucosaminyl 1-phosphate + UMP.
-!- The enzyme catalyzes a step in the biosynthesis of lipid A. -!- Formerly EC 3.6.1.n5.
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UniProtKB Entries (1)
A0A0H3C8Q1 |
A0A0H3C8Q1_CAUVN
Caulobacter vibrioides NA1000
UDP-2,3-diacylglucosamine pyrophosphatase LpxI
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PDB Structure
PDB | 4J6E |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
LpxI structures reveal how a lipid A precursor is synthesized.
Nat.Struct.Mol.Biol.
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