CATH Classification

Domain Context

CATH Clusters

Superfamily Metalloproteases ("zincins"), catalytic domain like
Functional Family Botulinum neurotoxin type B

Enzyme Information

3.4.24.68
Tentoxilysin.
based on mapping to UniProt P04958
Hydrolysis of 76-Gln-|-Phe-77 bond in synaptobrevin 2.
-!- Belongs to peptidase family M27.

UniProtKB Entries (1)

P04958
TETX_CLOTE
Clostridium tetani E88
Tetanus toxin

PDB Structure

PDB 4J1L
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Engineering Clostridia Neurotoxins with elevated catalytic activity
Guo, J., Pan, X., Zhao, Y., Chen, S.
Toxicon