CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.12 | Lyase 2-enoyl-coa Hydratase; Chain A, domain 2 |
|
1.10.12.10 | Lyase 2-enoyl-coa Hydratase, Chain A, domain 2 |
Domain Context
CATH Clusters
| Superfamily | Lyase 2-enoyl-coa Hydratase, Chain A, domain 2 |
| Functional Family | Methylthioacryloyl-CoA hydratase |
Enzyme Information
| 4.2.1.155 |
Methylthioacryloyl-CoA hydratase.
based on mapping to UniProt Q5LLW6
3-(methylthio)acryloyl-CoA + 2 H(2)O = acetaldehyde + methanethiol + CoA + CO(2).
-!- The enzyme is involved in the degradation of 3-(dimethylsulfonio)propanoate, an osmolyte produced by marine phytoplankton. -!- Isolated from the bacterium Ruegeria pomeroyi.
|
UniProtKB Entries (1)
| Q5LLW6 |
DMDD_RUEPO
Ruegeria pomeroyi DSS-3
Methylthioacryloyl-CoA hydratase
|
PDB Structure
| PDB | 4IZD |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal Structure of DmdD, a Crotonase Superfamily Enzyme That Catalyzes the Hydration and Hydrolysis of Methylthioacryloyl-CoA.
Plos One
|
