CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.367 | Hexokinase; domain 1 |
|
3.40.367.20 |
Domain Context
CATH Clusters
| Superfamily | 3.40.367.20 |
| Functional Family | Hexokinase 1 |
Enzyme Information
| 2.7.1.2 |
Glucokinase.
based on mapping to UniProt P35557
ATP + D-glucose = ADP + D-glucose 6-phosphate.
-!- A group of enzymes found in invertebrates and microorganisms highly specific for glucose.
|
UniProtKB Entries (1)
| P35557 |
HXK4_HUMAN
Homo sapiens
Glucokinase
|
PDB Structure
| PDB | 4IWV |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Optimising pharmacokinetics of glucokinase activators with matched triplicate design sets the discovery of AZD3651 and AZD9485
To be Published
|
