CATH Classification
Level | CATH Code | Description |
---|---|---|
1 | Mainly Alpha | |
1.10 | Orthogonal Bundle | |
1.10.10 | Arc Repressor Mutant, subunit A | |
1.10.10.10 | Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain |
Domain Context
CATH Clusters
Superfamily | Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain |
Functional Family | Friend leukemia integration 1 transcription factor |
Enzyme Information
UniProtKB Entries (1)
P11308 |
ERG_HUMAN
Homo sapiens
Transcriptional regulator ERG
|
PDB Structure
PDB | 4IRG |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Structural and dynamic studies of the transcription factor ERG reveal DNA binding is allosterically autoinhibited.
Proc.Natl.Acad.Sci.USA
|