CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.40 | 3-Layer(aba) Sandwich | |
3.40.1380 | Pyruvate Kinase; Chain: A, domain 1 | |
3.40.1380.20 | Pyruvate kinase, C-terminal domain |
Domain Context
CATH Clusters
Superfamily | Pyruvate kinase, C-terminal domain |
Functional Family | Pyruvate kinase |
Enzyme Information
2.7.1.40 |
Pyruvate kinase.
based on mapping to UniProt P30613
ATP + pyruvate = ADP + phosphoenolpyruvate.
-!- UTP, GTP, CTP, ITP and dATP can also act as donors. -!- Also phosphorylates hydroxylamine and fluoride in the presence of CO(2).
|
UniProtKB Entries (1)
P30613 |
KPYR_HUMAN
Homo sapiens
Pyruvate kinase PKLR
|
PDB Structure
PDB | 4IP7 |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Energetic Coupling between an Oxidizable Cysteine and the Phosphorylatable N-Terminus of Human Liver Pyruvate Kinase.
Biochemistry
|