CATH Classification

Domain Context

CATH Clusters

Superfamily Metal-dependent hydrolases
Functional Family 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase

Enzyme Information

4.1.1.45
Aminocarboxymuconate-semialdehyde decarboxylase.
based on mapping to UniProt Q8TDX5
2-amino-3-(3-oxoprop-1-en-1-yl)but-2-enedioate = 2-aminomuconate semialdehyde + CO(2).
-!- The product rearranges non-enzymically to picolinate.

UniProtKB Entries (1)

Q8TDX5
ACMSD_HUMAN
Homo sapiens
2-amino-3-carboxymuconate-6-semialdehyde decarboxylase

PDB Structure

PDB 4IGN
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Human alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase (ACMSD): A structural and mechanistic unveiling.
Huo, L., Liu, F., Iwaki, H., Li, T., Hasegawa, Y., Liu, A.
Proteins