CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.60 | Sandwich |
|
2.60.40 | Immunoglobulin-like |
|
2.60.40.10 | Immunoglobulins |
Domain Context
CATH Clusters
| Superfamily | Immunoglobulins |
| Functional Family |
Enzyme Information
| 3.4.22.37 |
Gingipain R.
based on mapping to UniProt P95493
Hydrolysis of proteins and small molecule substrates, with a preference for Arg in P1.
-!- Strongly activated by glycine and stabilized by calcium. -!- Belongs to peptidase family C25.
|
UniProtKB Entries (1)
| P95493 |
CPG2_PORGI
Porphyromonas gingivalis W83
Gingipain R2
|
PDB Structure
| PDB | 4IEF |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Porphyromonas gingivalis Virulence Factor Gingipain RgpB Shows a Unique Zymogenic Mechanism for Cysteine Peptidases.
J.Biol.Chem.
|