CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.40 | 3-Layer(aba) Sandwich | |
3.40.800 | Arginase; Chain A | |
3.40.800.10 | Ureohydrolase domain |
Domain Context
CATH Clusters
Superfamily | Ureohydrolase domain |
Functional Family | Arginase-1 |
Enzyme Information
3.5.3.1 |
Arginase.
based on mapping to UniProt P05089
L-arginine + H(2)O = L-ornithine + urea.
-!- Also hydrolyzes alpha-N-substituted L-arginines and canavanine.
|
UniProtKB Entries (1)
P05089 |
ARGI1_HUMAN
Homo sapiens
Arginase-1
|
PDB Structure
PDB | 4IE1 |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
2-Substituted-2-amino-6-boronohexanoic acids as arginase inhibitors.
Bioorg.Med.Chem.Lett.
|