CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.60 | 4-Layer Sandwich |
|
3.60.10 | Deoxyribonuclease I; Chain A |
|
3.60.10.10 | Endonuclease/exonuclease/phosphatase |
Domain Context
CATH Clusters
| Superfamily | Endonuclease/exonuclease/phosphatase |
| Functional Family | Tyrosyl-DNA phosphodiesterase 2 |
Enzyme Information
| 3.1.4.- |
Phosphoric diester hydrolases.
based on mapping to UniProt Q9JJX7
|
UniProtKB Entries (1)
| Q9JJX7 |
TYDP2_MOUSE
Mus musculus
Tyrosyl-DNA phosphodiesterase 2
|
PDB Structure
| PDB | 4GZ1 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Mechanism of repair of 5'-topoisomerase II-DNA adducts by mammalian tyrosyl-DNA phosphodiesterase 2.
Nat.Struct.Mol.Biol.
|
