CATH Classification

Domain Context

CATH Clusters

Superfamily Imidazole glycerol phosphate dehydratase; domain 1
Functional Family Imidazoleglycerol-phosphate dehydratase HisB

Enzyme Information

4.2.1.19
Imidazoleglycerol-phosphate dehydratase.
based on mapping to UniProt P9WML9
D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate = 3-(imidazol-4-yl)-2- oxopropyl phosphate + H(2)O.

UniProtKB Entries (1)

P9WML9
HIS7_MYCTU
Mycobacterium tuberculosis H37Rv
Imidazoleglycerol-phosphate dehydratase

PDB Structure

PDB 4GQU
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structures of the native, substrate- bound and inhibited forms of Mycobacterium tuberculosis imidazole glycerol phosphate dehydratase
Ahangar, M.S., Vyas, R., Nasir, N., Biswal, B.K.
Acta Crystallogr.,Sect.D