CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.40 | 3-Layer(aba) Sandwich | |
3.40.50 | Rossmann fold | |
3.40.50.720 | NAD(P)-binding Rossmann-like Domain |
Domain Context
CATH Clusters
Superfamily | NAD(P)-binding Rossmann-like Domain |
Functional Family | Alcohol dehydrogenase AdhP |
Enzyme Information
1.1.1.1 |
Alcohol dehydrogenase.
based on mapping to UniProt P39451
(1) A primary alcohol + NAD(+) = an aldehyde + NADH. (2) A secondary alcohol + NAD(+) = a ketone + NADH.
-!- Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol. -!- The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.
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UniProtKB Entries (1)
P39451 |
ADHP_ECOLI
Escherichia coli K-12
Alcohol dehydrogenase, propanol-preferring
|
PDB Structure
PDB | 4GKV |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Structure of Escherichia coli AdhP (ethanol-inducible dehydrogenase) with bound NAD.
Acta Crystallogr.,Sect.F
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