CATH Classification

Domain Context

CATH Clusters

Superfamily Survival protein SurE-like phosphatase/nucleotidase
Functional Family 5'/3'-nucleotidase SurE

Enzyme Information

3.1.3.6
3'-nucleotidase.
based on mapping to UniProt P66881
A 3'-ribonucleotide + H(2)O = a ribonucleoside + phosphate.
-!- Wide specificity for 3'-nucleotides.
3.1.3.5
5'-nucleotidase.
based on mapping to UniProt P66881
A 5'-ribonucleotide + H(2)O = a ribonucleoside + phosphate.
-!- Wide specificity for 5'-nucleotides.
3.6.1.11
Exopolyphosphatase.
based on mapping to UniProt P66881
(Polyphosphate)(n) + H(2)O = (polyphosphate)(n-1) + phosphate.

UniProtKB Entries (1)

P66881
SURE_SALTY
Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
5'/3'-nucleotidase SurE

PDB Structure

PDB 4GAD
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Dramatic Structural Changes Resulting from the Loss of a Crucial Hydrogen Bond in the Hinge Region Involved in C-Terminal Helix Swapping in SurE: A Survival Protein from Salmonella typhimurium.
Mathiharan, Y.K., Pappachan, A., Savithri, H.S., Murthy, M.R.N.
Plos One
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