CATH Classification

Domain Context

CATH Clusters

Superfamily Anticodon-binding domain
Functional Family histidine--tRNA ligase, cytoplasmic isoform X1

Enzyme Information

6.1.1.21
Histidine--tRNA ligase.
based on mapping to UniProt P12081
ATP + L-histidine + tRNA(His) = AMP + diphosphate + L-histidyl-tRNA(His).

UniProtKB Entries (1)

P12081
SYHC_HUMAN
Homo sapiens
Histidine--tRNA ligase, cytoplasmic

PDB Structure

PDB 4G85
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Internally Deleted Human tRNA Synthetase Suggests Evolutionary Pressure for Repurposing.
Xu, Z., Wei, Z., Zhou, J.J., Ye, F., Lo, W.S., Wang, F., Lau, C.F., Wu, J., Nangle, L.A., Chiang, K.P., Yang, X.L., Zhang, M., Schimmel, P.
Structure
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