CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.90 | Alpha-Beta Complex | |
3.90.226 | 2-enoyl-CoA Hydratase; Chain A, domain 1 | |
3.90.226.10 | 2-enoyl-CoA Hydratase; Chain A, domain 1 |
Domain Context
CATH Clusters
Superfamily | 2-enoyl-CoA Hydratase; Chain A, domain 1 |
Functional Family | Putative enoyl-CoA hydratase PaaB |
Enzyme Information
5.3.3.18 |
2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA isomerase.
based on mapping to UniProt P77467
2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA = 2-oxepin-2(3H)-ylideneacetyl- CoA.
-!- The enzyme catalyzes the reversible isomerization of 2-(1,2-epoxy- 1,2-dihydrophenyl)acetyl-CoA to the unusual unsaturated, oxygen- containing, seven-member heterocyclic enol ether 2-oxepin-2(3H)- ylideneacetyl-CoA, as part of an aerobic phenylacetate degradation pathway.
|
UniProtKB Entries (1)
P77467 |
PAAG_ECOLI
Escherichia coli K-12
1,2-epoxyphenylacetyl-CoA isomerase
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PDB Structure
PDB | 4FZW |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Protein-Protein Interactions in the beta-Oxidation Part of the Phenylacetate
Utilization Pathway. Crystal Structure of the PaaF-PaaG Hydratase-Isomerase Complex
J.Biol.Chem.
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