CATH Classification
Level | CATH Code | Description |
---|---|---|
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3 | Alpha Beta |
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3.30 | 2-Layer Sandwich |
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3.30.70 | Alpha-Beta Plaits |
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3.30.70.2440 |
Domain Context
CATH Clusters
Superfamily | 3.30.70.2440 |
Functional Family |
Enzyme Information
2.7.7.6 |
DNA-directed RNA polymerase.
based on mapping to UniProt Q859P9
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).
-!- Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. -!- Can initiate a chain de novo. -!- In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized. -!- See also EC 2.7.7.19 and EC 2.7.7.48.
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UniProtKB Entries (1)
Q859P9 |
RPOLV_BPN4
Escherichia virus N4
Virion DNA-directed RNA polymerase
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PDB Structure
PDB | 4FF3 |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Watching the Bacteriophage N4 RNA Polymerase Transcription by Time-dependent Soak-trigger-freeze X-ray Crystallography.
J.Biol.Chem.
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