CATH Domain 4fewD02

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.90	Alpha-Beta Complex
	3.90.1200	Aminoglycoside 3'-phosphotransferase; Chain: A, domain 2
	3.90.1200.10	Aminoglycoside phosphotransferase (APH), C-terminal lobe

Domain Context

CATH Clusters

Superfamily	3.90.1200.10
Functional Family

Enzyme Information

UniProtKB Entries (1)

B0VD92_ACIBY

Acinetobacter baumannii AYE

Aminoglycoside 3'-phosphotransferase AphA1-IAB

PDB Structure

PDB	4FEW
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structure-guided optimization of protein kinase inhibitors reverses aminoglycoside antibiotic resistance. Stogios, P.J., Spanogiannopoulos, P., Evdokimova, E., Egorova, O., Shakya, T., Todorovic, N., Capretta, A., Wright, G.D., Savchenko, A. Biochem.J.