CATH Classification

Domain Context

CATH Clusters

Superfamily 3.30.1120.10
Functional Family Galactosamine (N-acetyl)-6-sulfatase

Enzyme Information

3.1.6.4
N-acetylgalactosamine-6-sulfatase.
based on mapping to UniProt P34059
Hydrolysis of the 6-sulfate groups of the N-acetyl-D-galactosamine 6-sulfate units of chondroitin sulfate and of the D-galactose 6-sulfate units of keratan sulfate.

UniProtKB Entries (1)

P34059
GALNS_HUMAN
Homo sapiens
N-acetylgalactosamine-6-sulfatase

PDB Structure

PDB 4FDJ
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The Structure of Human GALNS Reveals the Molecular Basis for Mucopolysaccharidosis IV A.
Rivera-Colon, Y., Schutsky, E.K., Kita, A.Z., Garman, S.C.
J.Mol.Biol.